Product & ReviewsAntibodies

Anti-Human M-CSF - Biotin

Product Details

Cat. No.
M140
Clonality
Polyclonal
Host
Goat
Leinco Technologies

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Description

Macrophage colony-stimulating factor, or M-CSF, is a secreted cytokine which influences hemopoietic stem cells to differentiate into macrophages or other related cell types. M-CSF is a key regulator of cellular proliferation, differentiation, and survival of blood monocytes, tissue macrophages and their progenitor cells. It enhances cytotoxicity, superoxide production, phagocytosis, chemotaxis, and secondary cytokine production in monocytes and macrophages.1 It binds to the Colony stimulating factor 1 receptor. M-CSF is known as one of the factors essential for osteoclast development.2

Biological Information

  • Clonality: Polyclonal
  • Host: Goat
  • Reactivity: Human
  • Conjugate: Biotin
  • Gene: 1435

Handling

  • Quantity: 50 µg
  • Storage: The lyophilized, biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted biotin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.

Applications

  • ELISA (ELISA)
  • In Situ Hybridization (ISH)
  • Mass Cytometry (CyTOF)
  • Neutralization (Neut)
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