Product & ReviewsAntibodies
Anti-Human Phosphodiesterase V (PDE-5)
Product Details
- Cat. No.
- P164-0.1 mg
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Phosphodiesterases (PDEs) are a superfamily of enzymes that degrade the intracellular second messengers cyclic AMP and cyclic GMP. These enzymes are essential regulators of cyclic nucleotide signaling with diverse physiological functions. PDEs are drug targets for the treatment of disease states including heart failure, depression, asthma, inflammation and erectile dysfunction. Of the 12 PDE gene families, cGMP specific PDE5 carries out the principal cGMP hydrolyzing activity.1,2
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Clone: 29.29
- Conjugate: Purified
- Isotype: IgG1
Handling
- Quantity: 0.1 mg
- Storage: This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Applications
- Immunohistochemistry (IHC)
- Western Blotting (WB)