Product & ReviewsAntibodies
Anti-Human SIGIRR
Product Details
- Cat. No.
- S580
- Clonality
- Polyclonal
- Host
- Goat
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Description
Single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, also known as SIGIRR is a member of the IL-1 receptor family.1 It acts as a negative regulator of interleukin (IL)-1 and lipopolysaccharide (LPS) signaling.2 It also plays a critical role in gut homeostasis, intestinal inflammation, and colitis-associated tumorigenesis by maintaining the microbial tolerance of the colonic epithelium.3
Biological Information
- Clonality: Polyclonal
- Host: Goat
- Reactivity: Human
- Conjugate: Antigen Affinity Purified
- Gene: 59307
Handling
- Quantity: 100 µg, 25 µg
- Storage: The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Applications
- In Situ Hybridization (ISH)
- Mass Cytometry (CyTOF)
- Neutralization (Neut)
- Western Blotting (WB)