Product & ReviewsAntibodies

Anti-Human SMAC - Biotin

Product Details

Cat. No.
S592-50 µg
Clonality
Polyclonal
Host
Goat
Leinco Technologies

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Description

Second Mitochondria Derived Activator of Caspase (SMAC) is a mitochondrial apoptogenic protein that is released to the cytosol in response to diverse apoptotic stimuli, including commonly used chemotherapeutic drugs.1 SMAC promotes cytochrome-c dependent activation by eliminating the inhibition of IAP - a protein that negatively regulates apoptosis or programmed cell death.2

Biological Information

  • Clonality: Polyclonal
  • Host: Goat
  • Reactivity: Human
  • Conjugate: Biotin
  • Gene: 56616

Handling

  • Quantity: 50 µg
  • Storage: The lyophilized, biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted biotin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.

Applications

  • Immunohistochemistry (IHC)
  • Western Blotting (WB)
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