Anti-ICOSLG monoclonal antibody, clone MIH11 [FITC]
Product Details
- Cat. No.
- CABT-47445MH
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Mouse Anti-Human ICOSLG monoclonal antibody for FC. Mouse anti Human CD275 antibody, clone MIH11 detects CD275, also known as ICOS ligand (inducible T cell co-stimulator ligand). CD275 is a member of the B7 family, and interaction with its receptor CD278 (ICOS) plays an important role in T cell co-stimulation and inflammatory immune reactions. CD275 is expressed on activated B-cells, monocytes and dendritic cells and is also induced on non-lymphoid tissue cells such as endothelial cells, epithelial cells and muscle cells. CD275 has an important physiological role in the reactivation of effector/memory T cells on the endothelium, thus controlling entry of immune cells into inflamed tissue. The CD278-CD275 pathway is thought to be critical in the immune response to transplants, allergies and autoimmune diseases. MIH11 is reported to partially block the interaction between CD275 and CD278. Flow Cytometry Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. Applications：FC
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Conjugate: FITC
- Isotype: IgG1
- Gene: 23308
Handling
- Quantity: 100 μg
- Storage: in frost-free freezers is not recommended. This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)