Product & ReviewsAntibodies

Anti-IGFBP7 polyclonal antibody [Biotin]

Product Details

Cat. No.
CPBT-65633RH
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Creative Diagnostics

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Description

Rabbit anti-Human IGFBP7 polyclonal antibody for ELISA, WB. Rabbit anti Human IGFBP-7 antibody recognizes human IGFBP-7 (insulin-like growth factor binding protein-7), also known as mac25, a 256 amino acid secreted protein and member of a growing family of IGFBPs which regulate the biological activities and distribution of the insulin-like growth factors (IGFs), through binding to IGF-I and IGF-II. IGFBP-7 is widely expressed throughout normal tissues, but is also expressed in many tumour types at an increased or reduced level, and acts as a suppressor of breast and prostate cancer cell lines. IGFBP-7 inhibits IGF-induced differentiation of skeletal muscle (myogenesis) and has implications in bone formation, by its possible affects on the actions of parathyroid hormone (PTH) and cortisol. ELISA This biotinylated human IGFBP-7 antibody may be used in a direct ELISA or as the detection reagent in a sandwich ELISA. Applications:ELISA; WB

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human
  • Conjugate: Biotin
  • Isotype: Polyclonal IgG
  • Gene: 3490

Handling

  • Quantity: 50 μg
  • Storage: in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

Applications

  • Flow Cytometry (FC)
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