Product & ReviewsAntibodies

Anti-IL1RN polyclonal antibody [Biotin]

Product Details

Cat. No.
CPBT-65637RH
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Creative Diagnostics

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Description

Rabbit anti-Human IL1RN polyclonal antibody for ELISA, WB. This product specifically recognises human Interleukin-1 receptor antagonist (IL-1RA), a naturally occurring inflammatory inhibitor protein, produced by monocytes, macrophages, neutrophils, corneal epithelial cells and fibroblasts, which inhibits the activity of IL-1 alpha and IL-1 beta, by competitively blocking binding to cell surface receptors for IL-1. Genetic variations in IL-1RA gene (IL1RN) are associated with susceptibility to microvascular complications of diabetes type 4 (MVCD4), and IL-1RA has therapeutic applications in rheumatoid arthritis, asthma, psoriasis, sepsis, chronic myelogenous leukaemia and inflammatory bowel disease. ELISA This biotinylated human IL-1RA antibody may be used in a direct ELISA or as the detection reagent in a sandwich ELISA. Western Blotting This biotinylated human IL-1RA antibody may be used in Western Blotting applications under either reducing or non-reducing conditions. Applications:ELISA; WB

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human
  • Conjugate: Biotin
  • Isotype: Polyclonal IgG
  • Gene: 3557

Handling

  • Quantity: 50 μg
  • Storage: in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

Applications

  • Flow Cytometry (FC)
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