Product & ReviewsAntibodies

Anti-IL2RA monoclonal antibody, clone MEM-181 [Biotin]

Product Details

Cat. No.
CABT-48012MH
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Creative Diagnostics

The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our  Antibody Directory.

Description

Mouse Anti-Human IL2RA monoclonal antibody for FC. Mouse anti Human CD25, clone MEM-181 recognizes the 55kD alpha subunit of the human IL-2 receptor, also known as p55 or TAC antigen, CD25 is a type 1 transmembrane protein with two Sushi domains, also known as short concensus repeats (SCRs) or complement control protein (CCP) modules located within its extracellular domain. The IL-2 receptor exists in three forms. A high affinity form consiting of a non-covalently linked heterodimer composed of the alpha subunit (CD25) and the IL-2 receptor beta subunit also known as CD122 or p75, a medium affinity beta subunit (CD122) monomer or a low affinity alpha (CD25) subunit monomer. CD25 is expressed by activated T lymphocytes and activated B lymphocytes responding to antigen or mitogen stimulation. CD25 is also expressed in some thymocytes and oligodendrocytes. In disease, elevated expression of CD25 in noted in a number of chronic inflammatory conditions, tuberculoid leprosy patients demonstrate markedly elevated levels of circulating CD25high FoxP3+ regulatory T cells (T-regs). Elevated levels of CD25 antigen expression are often seen in cases of non-Hodgkin s lymphoma and diffuse large B cell lymphoma. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells in 100ul. Applications:FC

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Conjugate: Biotin
  • Isotype: IgG1
  • Gene: 3559

Handling

  • Quantity: 100 μg
  • Storage: in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

Applications

  • Flow Cytometry (FC)
Specificity rating
Sensitivity rating
Quality rating
Write your own review

Product Overview

Links