Rat Anti-Mouse ITGA2B monoclonal antibody for FC. Rat anti Mouse CD41 antibody, clone MWReg30 recognizes the mouse integrin alpha IIb subunit CD41. CD41 is a ~125kDa single pass type 1 transmembrane glycoprotein expressed by platelets, megakaryocytes, mast cells and hematopoietic progenitors. CD41 forms a heterodimer with CD61. The CD41/CD61 complex is important for platelet adhesion and aggregation acting as a receptor for many extracellular matrix proteins including fibronectin, thrombospondin and vitronectin. Rat anti mouse CD41, clone MWReg30 has been reported to inhibit PMA induced aggregation in vitro and to induce hypothermia in vivo. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells in 100ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors. Applications:FC
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Mouse
- Conjugate: Biotin
- Isotype: IgG1
- Gene: 16399
- Quantity: 100 μg
- Storage: in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.