Anti-ITGA4 monoclonal antibody, clone PS/2 [Biotin]
Product Details
- Cat. No.
- CABT-46336RM
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rat
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Description
Rat Anti-Mouse ITGA4 monoclonal antibody for FC. Rat anti Mouse CD49d monoclonal antibody, clone PS/2 recognizes murine alpha 4 integrin (CD49d), a ~150kDa single pass type I membrane glycoprotein that can associate with either beta 1 integrin (CD29) or beta 7 integrin to form heterodimers CD49d/CD29 (VLA-4) and alpha4/beta7 (LPAM-1) respectively. CD49d is expressed on most lymphocytes, granulocytes, monocytes and thymocytes. The primary ligands for CD49d are CD106 (VCAM-1), fibronectin and MAdCAM-1. Clone PS/2 has also been reported to block the binding of CD49d to its ligands. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells in 100ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors. Applications：FC
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Human, Mouse
- Conjugate: Biotin
- Isotype: IgG2b
- Gene: 16401
Handling
- Quantity: 100 μg
- Storage: Store at +4°C or at -20°C if preferred. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)