Anti-ITGA6 monoclonal antibody, clone NKI-GoH3 [Biotin]
Product Details
- Cat. No.
- CABT-46414RH
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rat
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Description
Rat Anti-Human ITGA6 monoclonal antibody for FC. Rat anti Human CD49f antibody, clone NKI-GoH3 recognizes CD49F (VLA-6 alpha chain), a 120kD cell surface glycoprotein that can form distinct complexes with CD29 (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells. Clone NKI-GoH3 reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukaemia cells (alpha-6 beta-1). In immunohistology the monoclonal antibody reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts.VLA-6 is an important mediator of cell binding to laminin. Studies suggest that clone NKI-GoH3 specifically blocks the binding of cells to the E8 fragment of laminin. Flow Cytometry Use 10ul of the suggested working dilution to label 106 platelets in 100ul. Applications：FC
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Cynomolgus Monkey, Dog (Canine), Human, Mouse, Pig (Swine), Sheep (Ovine)
- Conjugate: Biotin
- Isotype: IgG2a
- Gene: 3655
Handling
- Quantity: 100 μg
- Storage: in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)