Anti-ITGA6 monoclonal antibody, clone NKI-GoH3 [FITC]
Product Details
- Cat. No.
- CABT-46416RH
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rat
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Description
Rat Anti-Human ITGA6 monoclonal antibody for FC. Rat anti Human CD49f antibody, clone NKI-GoH3 recognizes CD49F (VLA-6 alpha chain), a 120kD cell surface glycoprotein that can form distinct complexes with CD29 (VLA beta-chain), resulting in the VLA-6 (alpha-6 beta-1) complex, which is expressed on human platelets, or with the beta-4 integrin resulting in the alpha-6 beta-4 complex which is expressed on various human epithelial cells. Clone NKI-GoH3 reacts with platelets, megakaryocytes, T lymphocytes and common Acute Lymphoblastic Leukaemia cells (alpha-6 beta-1). In immunohistology the monoclonal antibody reacts with epithelial cells of a variety of tissues, peripheral nerves, microvascular endothelial cells, placenta cyto- and syncytotrophoblasts.VLA-6 is an important mediator of cell binding to laminin. Studies suggest that clone NKI-GoH3 specifically blocks the binding of cells to the E8 fragment of laminin. Flow Cytometry Use 10ul of the suggested working dilution to label 106cells in 100ul. Applications：FC
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Cynomolgus Monkey, Dog (Canine), Human, Mouse, Pig (Swine), Sheep (Ovine)
- Conjugate: FITC
- Isotype: IgG2a
- Gene: 3655
Handling
- Quantity: 100 μg
- Storage: in frost-free freezers is not recommended. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)