Product & ReviewsAntibodies

Anti-ITGAL monoclonal antibody, clone I21/7 [R-PE]

Product Details

Cat. No.
CABT-45397RM
Type
Primary Antibody
Clonality
Monoclonal
Host
Rat
Creative Diagnostics

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Description

Rat Anti-Mouse ITGAL monoclonal antibody for FC. Rat anti Mouse CD11a antibody, clone I21/7 recognizes murine CD11a, a ~170-180kDa type I membrane glycoprotein, also known as the integrin alpha L subunit. CD11a is a member of the intergrin family of adhesion molecules. CD11a is expressed on all leucocytes and associates with CD18 to form a heterodimer at the cell surface. The CD11a/CD18 heterodimer binds to intercellular adhesion molecules (ICAM); ICAM1, ICAM-2 and ICAM-3 and is involved in cell-cell adhesion processes. Rat anti Mouse CD11a antibody, clone I21/7 is reported to block the cytolytic activity of cytotoxic T cell lines. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells in 100ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity fc receptors. Applications:FC

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Mouse
  • Conjugate: R-PE
  • Isotype: IgG2a
  • Gene: 16408

Handling

  • Quantity: 100 Tests
  • Storage: Store at +4°C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Applications

  • Flow Cytometry (FC)
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