Product & ReviewsAntibodies

Anti-ITGAM monoclonal antibody, clone 5C6 [R-PE]

Product Details

Cat. No.
CABT-45439RM
Type
Primary Antibody
Clonality
Monoclonal
Host
Rat
Creative Diagnostics

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Description

Rat Anti-Mouse ITGAM monoclonal antibody for FC. Rat anti Mouse CD11b antibody, clone 5C6 recognizes CD11b, also known as the integrin alpha M chain. CD11b is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. MCA711 immunoprecipitates a heterodimer of 165 and 95kD. Rat anti Mouse CD11b antibody, clone 5C6 exhibits various functional properties, reportedly inhibiting adhesion in vitro and inflammatory recruitment in vivo. Rat anti Mouse CD11b antibody, clone 5C6 also inhibits delayed hypersensitivity, potentiates bacterial infections and inhibits type 1 diabetes. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells in 100ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. Applications:FC

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Human, Mouse
  • Conjugate: R-PE
  • Isotype: IgG2b
  • Gene: 16409

Handling

  • Quantity: 100 Tests
  • Storage: Store at +4°C. DO NOT FREEZE This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Applications

  • Flow Cytometry (FC)
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