Anti-ITGAV monoclonal antibody, clone RMV-7 [R-PE]
Product Details
- Cat. No.
- CABT-48145RM
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Rat
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Description
Rat Anti-Mouse ITGAV monoclonal antibody for FC. Rat anti Mouse CD51 antibody, clone RMV-7 recognizes murine CD51, a 140 kD alpha subunit of the vitronectin receptor, which is otherwise known as the integrin alpha v chain. CD51 can form heterodimers at the cell surface with a variety of beta integrins including CD29 and CD61. Heterodimers of CD51/CD61 function as a receptor for vitronectin, and a wide array of RGD-containing proteins including fibronectin, fibrinogen, von Willebrand factor, laminin, thrombospondin and osteopontin. CD51/CD61 is primarily expressed on myeloid cells and activated T-cells. Alpha-V integrins may play a role in embryo implantation, angiogenesis and wound healing. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells in 100ul. Applications：FC
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Mouse
- Conjugate: R-PE
- Isotype: IgG1
- Gene: 16410
Handling
- Quantity: 100 Tests
- Storage: Store at +4°C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)