Anti-ITGAX monoclonal antibody, clone BU15 [R-PE]
Product Details
- Cat. No.
- CABT-45494MH
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Mouse Anti-Human ITGAX monoclonal antibody for FC. Mouse anti Human CD11c antibody, clone Bu15 recognizes the integrin alphax subunit (ITGAX), a 150kD glycoprotein also known as CD11 antigen-like family member C or Leu M5, CD11c is expressed by macrophages, monocytes, NK cells and most dendritic cells. CD11c is also expressed at a lower level by granulocytes. CD11c forms a heterodimeric integral membrane protein with the integrin beta 2 chain to form the leukocyte specific integrin inactivated-C3b receptor 4. CD11c interacts with a number of ligands including the G-P-R sequence in fibrinogen, ICAM-1, iC3b and Junctional adhesion molecule-like. CD11c is involved in cell-cell interactions during the inflammatory process and is important for monocyte adhesion and chemotaxis. CD11c also acts as a signalling receptor for polysaccharide. CD11c is expressed by hairy cell leukaemia cells. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells in 100ul. Applications：FC
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Cynomolgus Monkey, Human
- Conjugate: R-PE
- Isotype: IgG1
- Gene: 3687
Handling
- Quantity: 100 Tests
- Storage: Prior to reconstitution store at +4°C. Following reconstitution store at +4°C. This product should be stored undiluted. DO NOT FREEZE. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)