Product & ReviewsAntibodies

Anti-ITGB1 monoclonal antibody, clone 4B7R [Biotin]

Product Details

Cat. No.
CABT-45852MH
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Creative Diagnostics

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Description

Mouse Anti-Human ITGB1 monoclonal antibody for FC. Mouse anti Human CD29 monoclonal antibody, clone 4B7R recognizes the human integrin beta 1 subunit, also known as CD29, a ~130kDa (red) 115kDa (non-red) single pass type I transmembrane glycoprotein expressed by most leucocytes and mesenchymal stem cells. Integrin receptors are involved in the regulation of a variety of important biological functions, including embryonic development, wound repair, hemostasis and prevention of programmed cell death. They are also implicated in abnormal pathological states such as tumor directed angiogenesis, tumor cell growth, and metastasis. Surface expression of CD29 on human natural killer cells can be reduced by pretreatment with the glutathione-S-transferase inhibitor diethyl maleate. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells in 100ul. Immunohistology This product requires trypsin digestion pre-treatment of paraffin sections This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections. Applications:FC

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Conjugate: Biotin
  • Isotype: IgG1
  • Gene: 3688

Handling

  • Quantity: 100 μg
  • Storage: in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

Applications

  • Flow Cytometry (FC)
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