Anti-ITGB3 monoclonal antibody, clone HM beta 3.1 [R-PE]
Product Details
- Cat. No.
- CABT-48216HM
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Hamster
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Description
Hamster Anti-Mouse ITGB3 monoclonal antibody for FC. Hamster anti Mouse CD61 antibody, clone HM beta 3-1 recognizes the murine integrin beta 3 subunit (CD61), a 90kDa a type I membrane protein, which is expressed primarily on megakaryocytes, platelets, monocytes, macrophages, granulocytes and endothelial cells. CD61 associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) to form the platelet glycoprotein complex IIb/IIIa and the vitronectin receptor (VNR) respectively. The heterodimers formed with CD61 are receptor for a variety of ligands including fibrinogen, fibronectin, von Willebrands factor (vWF), vitronectin and thrombospondin. Hamster anti Mouse CD61 antibody, clone HM beta 3-1 is reported to partially inhibit the binding of CD61 to fibronectin. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells in 100ul. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors. Applications：FC
Biological Information
- Clonality: Monoclonal
- Host: Hamster
- Reactivity: Mouse, Rat
- Conjugate: R-PE
- Isotype: IgG
- Gene: 16416
Handling
- Quantity: 100 Tests
- Storage: Store at +4°C. DO NOT FREEZE This product should be stored undiluted. This product is photosensitive and should be protected from light.
Applications
- Flow Cytometry (FC)