Anti-ITGB3 monoclonal antibody, clone PM6/13 [Biotin]
Product Details
- Cat. No.
- CABT-48192MH
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Mouse Anti-Human ITGB3 monoclonal antibody for FC. Mouse anti Human CD61 antibody, clone PM6/13 recognizes a 105kD glycoprotein, which is the integrin beta 3 chain. This molecule associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) at the cell surface. CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51. CD61 is a receptor for fibrinogen, fibronectin, vWF, vitronectin and thrombospondin. Mouse anti Human CD61 antibody, clone PM6/13 has been reported to inhibit binding of fibronectin to activated human platelets. In functional studies it can be used to inhibit agonist induced platelet aggregation. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells or 100ul whole blood. Applications：FC
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Baboon, Dog (Canine), Ferret, Goat, Human, Mustelid
- Conjugate: Biotin
- Isotype: IgG1
- Gene: 3690
Handling
- Quantity: 100 μg
- Storage: in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)