Product & ReviewsAntibodies

Anti-ITGB3 monoclonal antibody, clone PM6/13 [R-PE]

Product Details

Cat. No.
CABT-48199MH
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Creative Diagnostics

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Description

Mouse Anti-Human ITGB3 monoclonal antibody for FC. Mouse anti Human CD61 antibody, clone PM6/13 recognizes a 105kD glycoprotein, which is the integrin beta 3 chain. This molecule associates with either the alpha IIb integrin (CD41) or the alpha V integrin (CD51) at the cell surface. CD61 is expressed on platelets and megakaryocytes in association with CD41, and on endothelial cells, monocytes, platelets and osteoclasts in association with CD51. CD61 is a receptor for fibrinogen, fibronectin, vWF, vitronectin and thrombospondin. Mouse anti Human CD61 antibody, clone PM6/13 has been reported to inhibit binding of fibronectin to activated human platelets. In functional studies it can be used to inhibit agonist induced platelet aggregation. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells in 100ul. Applications:FC

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Baboon, Dog (Canine), Ferret, Goat, Human, Mustelid
  • Conjugate: R-PE
  • Isotype: IgG1
  • Gene: 3690

Handling

  • Quantity: 100 Tests
  • Storage: Prior to reconstitution store at +4°C. Following reconstitution store at +4°C. This product should be stored undiluted. DO NOT FREEZE. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Applications

  • Flow Cytometry (FC)
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