MW 56,5000 (pI 5.3) intermediate filament polypeptide, keratin K10, detected by immunohistochemistry in the suprabasal layers of human epidermis (basal cells are negative). Useful for the recognition of keratinizing cells in squamous cell carcinoma of epidermis, lung, bladder, cervix, esophagus etc. Completely negative on non-stratified epithelia
- Clonality: Polyclonal
- Host: Guinea Pig
- Reactivity: Human, Mouse, Rat
- Antigen: synthetic peptide of human keratin K10 (formerly also designated cytokeratin 10; C-GS VGE SSS KGP RY), coupled to KLH
- Conjugate: unconjugated
- Quantity: 100 µL
- Storage: short term at 2-8°C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
- Specificity: 5
- Immunocytochemistry (ICC)
- Immunohistochemistry (IHC)
- Western Blotting (WB)