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Ks 17.E3 represents an excellent marker to distinguish myoepithelial cells (positive for K17) from luminal epithelium of various glands (mammary, sweat, salivary, bronchial, tracheal, laryngeal, esophageal) and benign from malignant forms of e.g. mammary gland tumors. In the epidermis suprabasal staining is found only in cornifying regions and in the outer root sheath of hair follicles.Tested reactivity on cultured cell lines: HeLa, A-431Tumors specifically detected: Benign tumors of mammary gland; most malignant forms of mammary tumors are negative for keratin K17