Ks 2.342.7.4 represents an excellent marker to study terminal epidermal differentiation. The mab is reactive with epidermal cells in uppermost suprabasal layers including scalp, foot and sole. It recognizes individual cells within epidermis of tongue and mamille (co-localization with keratin K10). It is also reactive on hyperkeratosis of diverse viral and genetic origin.The mab does not react with palate keratin K76.The actual clone designation of this antibody is Ks2.342.7.4
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Bovine, Human
- Antigen: synthetic peptide (N-terminal amino acids nos. 2-23) of human keratin K2 (MW 65,852)
- Clone: Ks2.342.7.4
- Conjugate: unconjugated
- Isotype: IgG1
- Quantity: 1 mL
- Storage: short term at 2-8°C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
- Immunocytochemistry (ICC)
- Immunohistochemistry (IHC)
- Western Blotting (WB)