C 22 represents an excellent marker for distinguishing carcinomas from all non-epithelial tumors. The antibody specifically reacts with keratins K5 and K8 present in nearly all epithelia. Polypeptide reacting: Mr 52 500, Mr 58 000 keratins (type II keratins K5 and K8; formerly also designated cytokeratins 5 and 8) of human epithelial cells. Epitope has been mapped to aa 353-367 on alpha helical rod domain of Keratin K8 (Waseeman et al
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Amphibia, Bovine, Human, Mouse, Pig (Swine), Hydra
- Antigen: human keratin K8, purified from SDS PAGE gel
- Clone: Ks 5+8.22/C22
- Conjugate: FITC
- Isotype: IgG1
- Quantity: 250 µL
- Storage: store at 2-8°C
- Immunocytochemistry (ICC)
- Immunohistochemistry (IHC)