Product & ReviewsAntibodies

anti-Keratin K5/K8 (Pan Epithelial) mouse monoclonal, C22, lyophilized, purified

Product Details

Cat. No.
61031
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
PROGEN

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Description

C 22 represents an excellent marker for distinguishing carcinomas from all non-epithelial tumors. The antibody specifically reacts with keratins K5 and K8 present in nearly all epithelia.Polypeptide reacting: Mr 52 500, Mr 58 000 keratins (type II keratins K5 and K8; formerly also designated cytokeratins 5 and 8) of human epithelial cells. Epitope has been mapped to aa 353-367 on alpha helical rod domain of Keratin K8 (Waseem et al., 2004)

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Amphibia, Bovine, Human, Mouse, Pig (Swine), Hydra
  • Antigen: human keratin K8, purified from SDS PAGE gel
  • Clone: Ks 5+8.22/C 22
  • Conjugate: unconjugated
  • Isotype: IgG1

Handling

  • Quantity: 50 µg
  • Storage: short term at 2-8°C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles

Applications

  • Immunocytochemistry (ICC)
  • Immunohistochemistry (IHC)
  • Western Blotting (WB)
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