Product & ReviewsAntibodies
anti-Keratin K5/K8 (Pan Epithelial) mouse monoclonal, C22, lyophilized, purified
Product Details
- Cat. No.
- 61031
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
C 22 represents an excellent marker for distinguishing carcinomas from all non-epithelial tumors. The antibody specifically reacts with keratins K5 and K8 present in nearly all epithelia.Polypeptide reacting: Mr 52 500, Mr 58 000 keratins (type II keratins K5 and K8; formerly also designated cytokeratins 5 and 8) of human epithelial cells. Epitope has been mapped to aa 353-367 on alpha helical rod domain of Keratin K8 (Waseem et al., 2004)
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Amphibia, Bovine, Human, Mouse, Pig (Swine), Hydra
- Antigen: human keratin K8, purified from SDS PAGE gel
- Clone: Ks 5+8.22/C 22
- Conjugate: unconjugated
- Isotype: IgG1
Handling
- Quantity: 50 µg
- Storage: short term at 2-8°C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Applications
- Immunocytochemistry (ICC)
- Immunohistochemistry (IHC)
- Western Blotting (WB)