Product & ReviewsAntibodies
anti-LDL Receptor mouse monoclonal, IgG-C7, lyophilized, purified
Product Details
- Cat. No.
- 61087
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Suitable for analysis of LDL receptor function in patients with familial hypercholesterolemia. The antibody recognizes an epitope in the region of repeat #1 of the ligand binding region. Addition of 15 nM antibody results in inhibition of half-maximal LDL-binding (Beisiegel et al. 1981). In human normal fibroblasts the antibody detects the 160 kD polypeptide (pI 4.3) and also in bovine adrenal gland (160 kD; pI 4.6) of LDL receptors (Beisiegel et al. 1982).Beisiegelt, U., Schneider, W. J
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Bovine, Human
- Antigen: purified bovine adrenal cortex LDL receptor
- Clone: IgG-C7
- Conjugate: unconjugated
- Isotype: IgG2b kappa
Handling
- Quantity: 50 µg
- Storage: short term at 2-8°C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
Applications
- Flow Cytometry (FC)
- Immunocytochemistry (ICC)