Product & ReviewsAntibodies

Anti-LEP polyclonal antibody [Biotin]

Product Details

Cat. No.
CPBT-65431RH
Type
Primary Antibody
Clonality
Polyclonal
Host
Rabbit
Creative Diagnostics

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Description

Rabbit Anti-Human LEP polyclonal antibody for ELISA; WB. This product recognises human leptin, a 16KDa major adipose-derived hormone and member of the leptin family, which plays a key role in appetite control and the regulation of energy expenditure. Secreted leptin associates with proteins within the bloodstream and is transported to the brain, where it inhibits or up-regulates the activity of neuropeptides such as neuropeptide Y (NPY) and alpha-melanocyte-stimulating hormone respectively. Leptin is a recognised marker of obesity, with a correlation between circulating levels of leptin and body fat mass, and defects in leptin production result in severe obesity. Regulators of leptin expression include insulin, cortisol, cAMP and thiazolidinediones. ELISA This biotinylated human leptin antibody may be used in a direct ELISA or as the detection reagent in a sandwich ELISA. Western Blotting This biotinylated human leptin antibody may be used in Western Blotting applications under either reducing or non-reducing conditions. Applications:ELISA; WB

Biological Information

  • Clonality: Polyclonal
  • Host: Rabbit
  • Reactivity: Human
  • Conjugate: Biotin
  • Isotype: Polyclonal IgG
  • Gene: 3952

Handling

  • Quantity: 50 μg
  • Storage: in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

Applications

  • Flow Cytometry (FC)
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