5A6 specifically reacts with the 85 kD b-chain of human LRP/a2MR which is expressed in a restricted spectrum of cell types (for a recent review cf. Herz & Strickland). A strong immunohistochemical reaction is seen in hepatocytes, tissue macrophages, subsets of neurones and astrocytes in the central nervous system, fibroblasts, smooth muscle cells, and monocyte-derived foam cells in atherosclerotic lesions in the arterial wall
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Hamster, Human, Mouse, Rabbit (Lapine), Rat
- Antigen: human LRP/alpha2MR
- Clone: 5A6
- Conjugate: unconjugated
- Isotype: IgG2b
- Quantity: 50 µg
- Storage: short term at 2-8°C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
- Flow Cytometry (FC)
- Immunohistochemistry (IHC)
- Western Blotting (WB)