8B8 specifically reacts with the 85 kD beta-chain of human LRP/alpha-2MR which is expressed in a restricted spectrum of cell types (Herz & Strickland 2001). A strong immunohistochemical reaction is seen in hepato-cytes, tissue macrophages, subsets of neurones and as-trocytes in the central nervous system, fibroblasts, smooth muscle cells, and monocyte-derived foam cells in athero-sclerotic lesions in the arterial wall
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Hamster, Human, Mouse, Rabbit (Lapine), Rat
- Antigen: human LRP/alpha-2MR
- Clone: 8B8
- Conjugate: unconjugated
- Isotype: IgG1
- Quantity: 50 µg
- Storage: short term at 2-8°C; long term storage in aliquots at - 20 °C; avoid freeze/ thaw cycles
- Flow Cytometry (FC)
- Immunocytochemistry (ICC)
- Immunohistochemistry (IHC)
- Western Blotting (WB)