Product & ReviewsAntibodies

Anti-LY9 monoclonal antibody, clone HLy9.1.25 [R-PE]

Product Details

Cat. No.
CABT-48420MH
Type
Primary Antibody
Clonality
Monoclonal
Host
Mouse
Creative Diagnostics

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Description

Mouse Anti-Human LY9 monoclonal antibody for FC. Mouse anti Human CD229 antibody, clone HLy9.1.25 recognizes the human cell surface antigen CD229 also known as T-lymphocyte surface antigen Ly-9 or SLAM family member 3. CD229 is a 608 amino acid single pass type I transmembrane glycoprotein of ~120kDa as evaluated by immunoprecipitation of cells transfected with the full length human CD229 cDNA. However immunoprecipitation of CD229 from Daudi cell lysates with dlone HLy9.1.25 yields bands of 120kDa corresponding to the full length CD229 and a 100kDa band attributed to an alternatively spliced isoform lacking the fourth Ig-like domain. Human CD299 is expressed on thymocytes, T-cells and B-cells. CD229 has also been described as a tumor associated antigen in chronic lymphocytic leukemia and has been implicated in the development of spontaneous autoantiboy production to nuclear antigens in mice and is potentially a target for the treatment of autoimmunity. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells in 100ul or 100ul whole blood. Applications:FC

Biological Information

  • Clonality: Monoclonal
  • Host: Mouse
  • Reactivity: Human
  • Conjugate: R-PE
  • Isotype: IgG1
  • Gene: 4063

Handling

  • Quantity: 100 Tests
  • Storage: Prior to reconstitution store at +4°C. Following reconstitution store at +4°C. DO NOT FREEZE. This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Applications

  • Flow Cytometry (FC)
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