Mouse Anti-Human MADCAM1 monoclonal antibody for FC. Mouse anti Human MAdCAM-1 antibody, clone 314G8 recognizes human mucosal addressin cell adhesion molecule 1 (MAdCAM-1) a 60kD cell surface protein that is involved in lymphocyte trafficking. MAdCAM-1 is expressed on high endothelial venules of Peyers patches and mesenteric lymph nodes. MAdCAM-1 expression has also been reported in the gut lamina propria but clone 314G8 does not recognize MAdCAM-1 in these tissues. Clone 314G8 reacts with the ligand-binding first Ig domain and reports suggest that a splice variant exists in the gut which is not recognized by clone 314G8. Clone 314G8 is reported to block the interaction of MAdCAM-1 with alpha 4 beta 7. Flow Cytometry Use 10ul of the suggested working dilution to label 106 cells in 100ul. Applications:FC
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Conjugate: R-PE
- Isotype: IgG1
- Gene: 8174
- Quantity: 100 Tests
- Storage: Store at +4°C. DO NOT FREEZE This product should be stored undiluted. This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.