Product & ReviewsAntibodies
anti-MHC-II-DRA mouse monoclonal, EBS-O-111, purified
Product Details
- Cat. No.
- 691664
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
MHC class II molecules are encoded by polymorphic MHC genes and consist of a non-covalent complex of an a and ß chain. Helper T lymphocytes bind antigenic peptides presented by MHC class II molecules. MHC class II molecules bind 13-18 amino acid antigenic peptides. Accumulating in endosomal/lysosomal compartments and on the surface of B-cells, HLA-DM and -DO molecules regulate binding of exogenous peptides to class II molecules (HLA-DR) by sustaining a conformation that favors peptide exchange
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Antigen: RAJI cells
- Clone: EBS-O-111
- Conjugate: unconjugated
- Isotype: IgG2a kappa
Handling
- Quantity: 1 mL (100 µg/ml)
- Storage: store at 2-8°C
Applications
- Flow Cytometry (FC)
- Immunohistochemistry (IHC)