Anti-Mica/Micb monoclonal antibody, clone 6D4 [FITC]
Product Details
- Cat. No.
- CABT-54422MH
- Type
- Primary Antibody
- Clonality
- Monoclonal
- Host
- Mouse
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Description
Mouse anti-Human Mica/Micb monoclonal antibody for FC. Mouse anti Human MICA/Micb antibody, clone 6D4 recognizes nonclassical MHC class I chain A (MICA) and nonclassical MHC class I chain MICB (MICB). MICA and MICB are stress inducible antigens, which are closely related and appear functionally indistinguishable. MICA and MICB are ligands for NKG2D, an activating receptor on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. MICA is principally expressed on intestinal epithelium, and several epithelial tumours. Expression may be induced to high surface levels by heat shock, oxidative stress, and virus infection. Clone 6D4 is reported to inhibit the cytotoxicity of NK cells stimulated by IFN alpha-treated dendritic cells. Flow Cytometry Use 10ul of the suggested working dilution to label 1x106 cells in 100ul. Applications：FC
Biological Information
- Clonality: Monoclonal
- Host: Mouse
- Reactivity: Human
- Conjugate: FITC
- Isotype: IgG2a
- Gene: 4277
Handling
- Quantity: 100 μg
- Storage: in frost-free freezers is not recommended. This product should be stored undiluted. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Applications
- Flow Cytometry (FC)