Product & ReviewsAntibodies

Anti-Mouse CD25 - Biotin

Product Details

Cat. No.
C1190
Clonality
Monoclonal
Host
Rat
Leinco Technologies

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Description

CD25, a 55 kD type I transmembrane glycoprotein, has been shown to play roles in lymphocyte differentiation, activation, and proliferation. Many resting memory T cells constitutively express IL2RA. It functions as the receptor for HTLV-1, resulting in its expression on neoplastic cells in adult T cell lymphoma/leukemia. CD25 (sIL-2R) has been used to track disease progression. Some additional clinical applications include Chagas disease, a disease characterized by a decline of CD25 expression on immune cells, and Multiple sclerosis, in which treatments with mAbs target CD25.

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Mouse
  • Antigen: CD25 is expressed in activated T cells and B cells, thymocyte subset, pre-B cells, T regulatory cells.
  • Clone: PC61
  • Conjugate: Biotin
  • Isotype: IgG1 λ

Handling

  • Quantity: 100 µg, 500 µg
  • Storage: This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.

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