Product & ReviewsAntibodies

Anti-Mouse CD25 - Purified <i>In vivo </i>GOLD™ Functional Grade

Product Details

Cat. No.
C1194- 100 mg
Clonality
Monoclonal
Host
Rat
Leinco Technologies

The supplier does not provide quotations for this antibody through SelectScience. You can search for similar antibodies in our  Antibody Directory.

Description

CD25, a 55 kD type I transmembrane glycoprotein, has been shown to play roles in lymphocyte differentiation, activation, and proliferation. Many resting memory T cells constitutively express IL2RA. It functions as the receptor for HTLV-1, resulting in its expression on neoplastic cells in adult T cell lymphoma/leukemia. CD25 (sIL-2R) has been used to track disease progression. Some additional clinical applications include Chagas disease, a disease characterized by a decline of CD25 expression on immune cells, and Multiple sclerosis, in which treatments with mAbs target CD25.

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Mouse
  • Antigen: CD25 is expressed in activated T cells and B cells, thymocyte subset, pre-B cells, T regulatory cells.
  • Clone: PC61
  • Conjugate: GOLD, Low Endotoxin Functional Formulation
  • Isotype: IgG1 λ
  • Gene: 16184

Handling

  • Quantity: 100 mg
  • Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

Applications

    Specificity rating
    Sensitivity rating
    Quality rating
    Write your own review

    Product Overview

    Links