Product & ReviewsAntibodies

Anti-Mouse CD25 - Purified <i>In vivo </i>PLATINUM™ Functional Grade

Product Details

Cat. No.
C2845- 50 mg
Clonality
Monoclonal
Host
Rat
Leinco Technologies

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Description

CD25, a 55 kD type I transmembrane glycoprotein, has been shown to play roles in lymphocyte differentiation, activation, and proliferation. Many resting memory T cells constitutively express IL2RA. It functions as the receptor for HTLV-1, resulting in its expression on neoplastic cells in adult T cell lymphoma/leukemia. CD25 (sIL-2R) has been used to track disease progression. Some additional clinical applications include Chagas disease, a disease characterized by a decline of CD25 expression on immune cells, and Multiple sclerosis, in which treatments with mAbs target CD25.

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Mouse
  • Antigen: CD25 is expressed in activated T cells and B cells, thymocyte subset, pre-B cells, T regulatory cells.
  • Clone: PC61
  • Conjugate: Low Endotoxin Functional Formulation, PLATINUM
  • Isotype: IgG1 λ
  • Gene: 16584

Handling

  • Quantity: 50 mg
  • Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

Applications

  • ELISA (ELISA)
  • Immunohistochemistry (IHC)
  • Immunoprecipitation (IP)
  • In Situ Hybridization (ISH)
  • Mass Cytometry (CyTOF)
  • Western Blotting (WB)
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