Product & ReviewsAntibodies

Anti-Mouse CD252 (OX40L) - Purified <i>In vivo </i>GOLD™ Functional Grade

Product Details

Cat. No.
C2336-1.0 mg
Clonality
Monoclonal
Host
Rat
Leinco Technologies

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Description

CD252 is a 35 kD member of the TNF superfamily and is the ligand for OX-40, which is primarily found on activated T cells. The CD252/OX-40 pair contributes to B-cell and T-cell interaction during the immune response. Both proliferative and IL-2 production responses of activated T cells are enhanced via OX-40 antigen stimulation, while proliferation and Ig secretion by activated B cells is enhanced via CD252 stimulation. Hence, because both T cells and B cells are activated in cross-linking, the CD252/OX-40 pair is considered reciprocally costimulatory.

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Mouse
  • Antigen: CD252 is expressed on activated B cells and antigen presenting cells.
  • Clone: RM134L
  • Conjugate: GOLD, Low Endotoxin Functional Formulation
  • Isotype: IgG2b κ
  • Gene: 22164

Handling

  • Quantity: 1.0 mg
  • Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

Applications

  • In Situ Hybridization (ISH)
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