Product & ReviewsAntibodies

Anti-Mouse CD278 (ICOS) - Biotin

Product Details

Cat. No.
C2259-50 µg
Clonality
Monoclonal
Host
Rat
Leinco Technologies

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Description

CD278 (ICOS) belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers (47-57kD) and enhances all basic T cell responses to a foreign antigen, specifically proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B cells. ICOS signaling is also an important regulator for T cell homeostasis. ICOS plays a role in humoral immune response and is thought to have involvement in the development of Th2 cells and to play a protective role in inflammatory autoimmune diseases.

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Mouse
  • Antigen: ICOS is expressed on activated T cells and APCs including splenic B cells, dendritic cells, and macrophages.
  • Clone: 7E.17G9
  • Conjugate: Biotin
  • Isotype: IgG2b
  • Gene: 54167

Handling

  • Quantity: 50 µg
  • Storage: This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.

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