Product & ReviewsAntibodies
Anti-Mouse CD28 - Purified
Product Details
- Cat. No.
- C243- 500 µg
- Clonality
- Monoclonal
- Host
- Syrian 9
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Description
CD28 is a 44 kD glycoprotein and a member of the Ig superfamily. In its capacity as a costimulatory receptor, CD28 produces co-stimulatory signals necessary for T cell activation and survival. CD28 is the only B7 receptor constitutively expressed on naive T cells. Without having this CD28/B7 interaction, T cells will fail to respond to their specific antigen when coming in contact with an MHC/antigen complex and thus, are said to be anergic.
Biological Information
- Clonality: Monoclonal
- Host: Syrian 9
- Reactivity: Mouse
- Antigen: CD28 is expressed on thymocytes, CD4+, CD8+ peripheral T cells, NK cells.
- Clone: 37.51
- Conjugate: Purified
- Isotype: IgG
- Gene: 12487
Handling
- Quantity: 500 µg
- Storage: This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Applications
- Fluorescent Assay (FA)
- In Situ Hybridization (ISH)
- Western Blotting (WB)