CD28 is a 44 kD glycoprotein and a member of the Ig superfamily. In its capacity as a costimulatory receptor, CD28 produces co-stimulatory signals necessary for T cell activation and survival. CD28 is the only B7 receptor constitutively expressed on naive T cells. Without having this CD28/B7 interaction, T cells will fail to respond to their specific antigen when coming in contact with an MHC/antigen complex and thus, are said to be anergic.
- Clonality: Monoclonal
- Host: Syrian 9
- Reactivity: Mouse
- Antigen: CD28 is expressed on thymocytes, CD4+, CD8+ peripheral T cells, NK cells.
- Clone: 37.51
- Conjugate: GOLD, Low Endotoxin Functional Formulation
- Isotype: IgG
- Gene: 12487
- Quantity: 1.0 mg
- Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
- In Situ Hybridization (ISH)
