Product & ReviewsAntibodies

Anti-Mouse CD28 - Purified <i>In vivo </i>GOLD™ Functional Grade

Product Details

Cat. No.
C379- 100 mg
Clonality
Monoclonal
Host
Syrian 9
Leinco Technologies

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Description

CD28 is a 44 kD glycoprotein and a member of the Ig superfamily. In its capacity as a costimulatory receptor, CD28 produces co-stimulatory signals necessary for T cell activation and survival. CD28 is the only B7 receptor constitutively expressed on naive T cells. Without having this CD28/B7 interaction, T cells will fail to respond to their specific antigen when coming in contact with an MHC/antigen complex and thus, are said to be anergic.

Biological Information

  • Clonality: Monoclonal
  • Host: Syrian 9
  • Reactivity: Mouse
  • Antigen: CD28 is expressed on thymocytes, CD4+, CD8+ peripheral T cells, NK cells.
  • Clone: 37.51
  • Conjugate: GOLD, Low Endotoxin Functional Formulation
  • Isotype: IgG
  • Gene: 12487

Handling

  • Quantity: 100 mg
  • Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

Applications

  • In Situ Hybridization (ISH)
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