CD3ε is a 20kDa subunit of the TCR complex and is a transmembrane T-cell surface glycoprotein that belongs to the Ig superfamily. It is one of five polypeptide chains that form the TCR complex by associating with the CD3δ, γ and ζ chains, in addition to the TCR α/β or γ/δ chains. CD3 is involved in TCR signaling, enumeration of immunocompetent T-lymphocytes in peripheral blood, and signal transduction during antigen recognition.
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Mouse
- Antigen: CD3 is expressed on human peripheral blood lymphocytes, splenic lymphocytes, and the majority of T-CLL and T-ALL cells.
- Clone: 17A2
- Conjugate: GOLD, Low Endotoxin Functional Formulation
- Isotype: IgG2b κ
- Gene: 12502
- Quantity: 1.0 mg
- Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
- Blocking (BA)
- Immunofluorescence (IF)
- Immunohistochemistry (IHC)
- In Situ Hybridization (ISH)
