Product & ReviewsAntibodies
Anti-Mouse CD32/CD16 - PE
Product Details
- Cat. No.
- C250-0.1 mg
- Clonality
- Monoclonal
- Host
- Rat
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Description
CD16 is expressed in two forms: CD16a and CD16b. CD16a (γRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. CD16b (γRIIIB) is a 48 kD GPI-anchored protein whose extracellular domain is over 95% homologous to that of CD16a. CD16 regulates both phagocytosis and antibody-dependent cell-mediated cytotoxicity. It has been reported that CD16 is involved in Natural Killer Cell activation and plays a role in signal transduction. The receptors, CD32 (γRIII) and CD16 (γRII), are 40-60 kD and bind antibody-antigen immune complexes and mediate adaptive immune responses.
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Mouse
- Antigen: These receptors are present on B cells, monocyte/macrophages, NK cells, neutrophils, mast cells and dendritic cells.
- Clone: 2.4G2
- Conjugate: R-phycoerythrin (PE)
- Isotype: IgG1
- Gene: 14130 14131
Handling
- Quantity: 0.1 mg
- Storage: This R-PE conjugate is stable when stored at 2-8°C. Do not freeze.
Applications
- In Situ Hybridization (ISH)