Product & ReviewsAntibodies
Anti-Mouse CD3ε (Clone 145-2C11) - Purified <i>In vivo </i>PLATINUM™ Functional Grade
Product Details
- Cat. No.
- C2280
- Clonality
- Monoclonal
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Description
CD3ε is a 20kDa subunit of the TCR complex and is a transmembrane T-cell surface glycoprotein that belongs to the Ig superfamily. It is one of five polypeptide chains that form the TCR complex by associating with the CD3δ, γ and ζ chains, in addition to the TCR α/β or γ/δ chains. CD3 is involved in TCR signaling, enumeration of immunocompetent T-lymphocytes in peripheral blood, and signal transduction during antigen recognition.
Biological Information
- Clonality: Monoclonal
- Reactivity: Mouse
- Antigen: CD3ε is primarily expressed on mature T cells and NK-T cells and at different levels on differentiation-dependent thymocytes.
- Clone: 145-2C11
- Conjugate: Low Endotoxin Functional Formulation, PLATINUM
- Isotype: IgG
- Gene: 12501
Handling
- Quantity: 1.0 mg, 100 mg, 25 mg, 5.0 mg, 50 mg
- Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Applications
- Immunohistochemistry (IHC)
- Western Blotting (WB)