Product & ReviewsAntibodies
Anti-Mouse CD4 (Clone GK1.5) - Purified <i>In vivo </i>PLATINUM™ Functional Grade
Product Details
- Cat. No.
- C2838
- Clonality
- Monoclonal
- Host
- Rat
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Description
CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. CD4 interacts with class II molecules of the major histocompatibility complex (MHC) enhancing the signal for T-cell activation.6
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Mouse
- Antigen: The CD4/L3T4 antigen is expressed by the helper/inducer subset of mouse T-cells. The antigen is present on approximately 80% of thymocytes, 20% of spleen cells and 60% of lymph node cells. The expression of L3T4 correlates with class II MHC antigen reactivity on cloned T-cell lines.
- Clone: GK1.5
- Conjugate: Low Endotoxin Functional Formulation, PLATINUM
- Isotype: IgG2b κ
- Gene: 12504
Handling
- Quantity: 1.0 mg, 100 mg, 25 mg, 5 mg, 50 mg
- Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Applications
- Immunohistochemistry (IHC)
- In Situ Hybridization (ISH)
- Western Blotting (WB)