Product & ReviewsAntibodies

Anti-Mouse CD4 (Clone GK1.5) - Purified <i>In vivo </i>PLATINUM™ Functional Grade

Product Details

Cat. No.
C2838- 100 mg
Clonality
Monoclonal
Host
Rat
Leinco Technologies

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Description

CD4 (cluster of differentiation 4) is a glycoprotein expressed on the surface of T helper cells, regulatory T cells, monocytes, macrophages, and dendritic cells. CD4 interacts with class II molecules of the major histocompatibility complex (MHC) enhancing the signal for T-cell activation.6

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Mouse
  • Antigen: The CD4/L3T4 antigen is expressed by the helper/inducer subset of mouse T-cells. The antigen is present on approximately 80% of thymocytes, 20% of spleen cells and 60% of lymph node cells. The expression of L3T4 correlates with class II MHC antigen reactivity on cloned T-cell lines.
  • Clone: GK1.5
  • Conjugate: Low Endotoxin Functional Formulation, PLATINUM
  • Isotype: IgG2b κ
  • Gene: 12504

Handling

  • Quantity: 100 mg
  • Storage: Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

Applications

  • Immunohistochemistry (IHC)
  • In Situ Hybridization (ISH)
  • Western Blotting (WB)
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