Anti-Mouse CD62L - DyLight® 488
Product Details
- Cat. No.
- C2095- 200 µg
- Clonality
- Monoclonal
- Host
- Rat
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Description
CD62L is a 75-95 kD glycoprotein which is also known as L-selectin, Ly-22, LAM-1, and MEL-14. It is a member of the selectin family and is expressed on the majority of B and naïve T cells, a subset of memory T cells, monocytes, granulocytes, most thymocytes, and a subset of NK cells. CD62L is important in lymphocyte homing to high endothelial venules (HEV) in peripheral lymph nodes and leukocyte "rolling" on activated endothelium. CD62L also contributes to neutrophil emigration at inflammatory sites. CD62L is rapidly shed from lymphocytes and neutrophils upon cellular activation and the expression levels of CD62L (in conjunction with other markers) have been used to distinguish naïve, effector, and memory T cells.
Biological Information
- Clonality: Monoclonal
- Host: Rat
- Reactivity: Mouse
- Clone: MEL-14
- Conjugate: DyLight® 488
- Isotype: IgG2a
- Gene: 20343
Handling
- Quantity: 200 µg
- Storage: This DyLight® 488 conjugate is stable when stored at 2-8°C. Do not freeze.
Applications
- In Situ Hybridization (ISH)