Product & ReviewsAntibodies

Anti-Mouse CD70 - APC

Product Details

Cat. No.
C2405- 25 µg
Clonality
Monoclonal
Host
Rat
Leinco Technologies

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Description

CD70 is a 30-33 kD type II transmembrane glycoprotein and a member of the TNF superfamily. CD70 is the ligand for CD27; the binding of which delivers costimulatory signals to T cells and NK cells. CD70 is expressed on highly activated lymphocytes characteristic of T- and B-cell lymphomas. Because normal lymphocytes have low CD70 expression, it has been suggested that anti-CD70 antibodies may be a possible treatment for CD70 positive lymphomas. CD70-specific antibodies are currently under investigation for the treatment of hematological malignancies and renal cell carcinoma.

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Mouse
  • Antigen: CD70 is expressed by highly activated lymphocytes as found in T-cell and B-cell lymphomas.
  • Clone: FR70
  • Conjugate: Allophycocyanin (APC)
  • Isotype: IgG2b
  • Gene: 21948

Handling

  • Quantity: 25 µg
  • Storage: This APC conjugate is stable when stored at 2-8°C. Do not freeze.

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