Product & ReviewsAntibodies
Anti-Mouse CD86 - Biotin
Product Details
- Cat. No.
- B611-50 µg
- Clonality
- Polyclonal
- Host
- Goat
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Description
CD86 is an 80kD Ig superfamily member that is involved in immunoglobulin class-switching and activation of NK cell-mediated cytotoxicity. CD80 is closely related to, and works in tandem with CD86 to prime T- cells. CD86 is expressed earlier in the immune response than CD80. The ligation of CD28 on T cells with CD80 and CD86 on APCs co-stimulates T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD86 can also bind to CTLA-4 to deliver an inhibitory signal to T cells.
Biological Information
- Clonality: Polyclonal
- Host: Goat
- Reactivity: Mouse
- Antigen: CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes.
- Conjugate: Biotin
- Gene: 12524
Handling
- Quantity: 50 µg
- Storage: The lyophilized, biotinylated antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for up to twelve months from date of receipt. The reconstituted biotin conjugate can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted conjugate, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Applications
- Western Blotting (WB)