Product & ReviewsAntibodies

Anti-Mouse CD86 - PE

Product Details

Cat. No.
C2162
Clonality
Monoclonal
Host
Rat
Leinco Technologies

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Description

CD86 is an 80kD Ig superfamily member that is involved in immunoglobulin class-switching and activation of NK cell-mediated cytotoxicity. CD80 is closely related to, and works in tandem with CD86 to prime T- cells. CD86 is expressed earlier in the immune response than CD80. The ligation of CD28 on T cells with CD80 and CD86 on APCs co-stimulates T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD86 can also bind to CTLA-4 to deliver an inhibitory signal to T cells.

Biological Information

  • Clonality: Monoclonal
  • Host: Rat
  • Reactivity: Mouse
  • Antigen: CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes.
  • Clone: GL1
  • Conjugate: R-phycoerythrin (PE)
  • Isotype: IgG2a κ
  • Gene: 12524

Handling

  • Quantity: 100 µg, 200 µg, 50 µg
  • Storage: This R-PE conjugate is stable when stored at 2-8°C. Do not freeze.

Applications

  • Blocking (BA)
  • Depletion (Dep)
  • Fluorescent Assay (FA)
  • In Situ Hybridization (ISH)
  • Mass Cytometry (CyTOF)
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